Research Assistant - Immunogenomics
Darlinghurst, Sydney, NSW
At Garvan our research is focused upon understanding the role of genes and molecular and cellular processes in health and disease as the basis for developing future preventions, treatments and cures. Our scientists are researchers who work towards making significant breakthroughs in scientific discovery to positively impact human health.
About the Project
The Immunology Division has established an Immunogenomics laboratory to apply massively parallel sequencing and genomics technologies to understanding the pathogenesis of immune system diseases including autoimmunity, immune deficiency, and cancer of immune cells. In collaboration with The Kinghorn Centre for Clinical Genomics, other laboratories in the Garvan Institute, and a network of clinical, laboratory and computation collaborators, the laboratory provides access to contemporary techniques for detecting and evaluating mutations revealed by whole genome sequencing, deep RNA sequencing, or single cell sequencing. This technology will be applicable to the study of both human tissue and animal models of disease.
We currently have a new opportunity for a Research Assistant to join the Immunogenomics laboratory supporting Dr Joanne Reed to analyse mouse models of autoimmunity and gene expression profiles and high parameter flow cytometric patterns of human lymphocytes.
Key responsibilities will include:
- Working with experimental mouse models of autoimmunity, including handling, injections and tissue dissection
- Maintain and monitor mouse colonies
- Perform high parameter flow cytometric cell sorting and analysis of precious lymphocyte subpopulations from humans and mice
- Design vectors to express mutant and wild-type versions of genes and antibodies in human or mouse cells, for example by transient or stable transfection or retroviral transduction
- Measure the activity of expressed genes or antibodies by methods such as qPCR, ELISA, luciferase assays, western blotting, flow cytometry or confocal microscopy
This full-time position is offered on a 1-year fixed term in the first instance.
You will possess the following key skills and experience:
- BSc Hons with majors in Molecular Biology, Biological Sciences, Immunology or equivalent
- Desire to pursue a PhD in Immunology
- Expertise in flow cytometry methods, expression or analysis of antibodies, PCR, or transfection of cells would be an advantage
- Expertise in animal handling an advantage
- Experience of managing own research project
- Effective communication skills, able to take active part in group discussions and strategy meetings with senior members of the research team
- Presentation skills at scientific meetings or oral presentations to the research group
- Ability to assess and organise resources, and plan and progress work activities
- Research, plan and execute experiments and analyse and interpret data generated
How to Apply
All applications must be submitted via the Garvan Careers site via the link below. Applications from other sites/channels will unfortunately not be considered.
Your application should include:
- A cover letter addressing the selection criteria above
- Your resume including 3 referees
- Copies of relevant qualifications / academic transcripts
Only applicants with working rights in Australia are eligible to apply for this role.
8 June 2018.
As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.